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The AI and sharks can unlock cancer and long life.



"Recent studies on the Greenland shark, the longest-living vertebrate, reveal that its stable muscle metabolic activity across different ages may be key to its extraordinary longevity. Led by Mr. Ewan Camplisson from the University of Manchester, the research not only challenges previous beliefs that attribute the shark’s lifespan to its cold environment and minimal movement but also opens potential avenues for conservation strategies and human cardiovascular research." (ScitechDaily, Experimental Research on the World’s Longest-Living Vertebrate Reveals New Anti-Aging Secrets)

The new AI-based systems can unlock the secret code of the DNA. AI is the ultimate tool for DNA analysis, and it can find new details from humans and other species' genetic codes. The AI uncovered things like ancient viruses that turned part of our DNA can cause cancer. The most interesting thing is that the AI that breaks genetic secrets can bring how some species can live hundreds of years, and others die in age, under 100 years. 

The Greenland shark can live 400-500 years, and their ability to repair their DNA is one of the things that the AI can solve. If researchers find that genome and transfer it to humans. That would allow researchers to extend our lifetime. The thing is that the AI might quite soon tell, how those Greenland Sharks can live so long time. Another thing that makes great white sharks, and Greenland sharks interesting is that those sharks have a very low cancer rate. 

"GROVER, a new large language model trained on human DNA by researchers at Dresden University of Technology’s Biotechnology Center, can decode complex genomic information by treating DNA as a language. This innovative tool holds the potential to revolutionize genomics and accelerate personalized medicine." (ScitechDaily, Cracking the Code of Life: New AI Model Learns DNA’s Hidden Language)

It's possible. That shark's DNA can help us to create a cure for cancer. We know that the evolution of sharks is slow, but that doesn't tell why there is so little cancer in the shark population. Some researchers say, that the shark's ability to live so long and the ability to resist cancer is a risk to them. 

When researchers talk about sharks that can resist cancer, they normally mean great white sharks and Greenland sharks. All sharks can't resist cancer.  Research with those things mainly happens using cell cultures. The fact is that eating sharks doesn't make anybody younger. The requirement for that kind of therapy is that the DNA bite can be connected in the human DNA. 

"Images (a) and (b) show the tumor on the great white shark, while (c) and (d) show tumors on the bronze whaler shark.Andrew Fox and Sam Cahir" (NBC News, Forget the myth, sharks DO get cancer -- even great whites)

Can foreign objects, high carcinogen levels, or some kind of nuclear waste cause this kind of tumor? 

In 2013, researchers saw a tumor in the great white shark's lower jaw. That is the first documented case in history. Maybe a foreign object in the shark's body causes that kind of tumor. That object can be the fisherman's hook. Tumors are not a very common thing in great white sharks. The fact is, anyway, that the Blacktip reef sharks have tumors. The really interesting shark species are Greenland sharks and great white sharks. 

During the Cold War, the Soviet Union and the USA buried lots of chemicals and radioactive waste in the Barents Sea and maybe in the Antarctic Sea. Maybe, that tumor on the shark's skin is caused by contact with carcinogens or radioactive material. In the last case, that means some of the capsules where the radioactive material is closed can leak. The great white sharks live in large areas. That means they can bite barrels with radioactive or carcinogens involving in a long way from the exposure. 

Maybe a very high carcinogen or level can cause tumors for the great white sharks. But if those carcinogens are very high levels, that doesn't mean that shark gets tumors in normal natural carcinogen levels. Maybe the leak in barrels where the highly radioactive material closed before they dropped into the deep sea can cause a situation in which sharks can have contact with things like plutonium or some other highly radioactive isotopes. Maybe the shark with the tumor tasted some kind of radioactive materials, that the Soviets buried in the Barents Sea. 


https://www.bbc.com/news/newsbeat-47291697


https://geographical.co.uk/news/sharks-slow-evolution-explains-low-cancer-rates


https://www.nbcnews.com/sciencemain/forget-myth-sharks-do-get-cancer-even-great-whites-2d11703500


https://scitechdaily.com/ancient-viruses-hidden-in-your-dna-fuel-modern-day-cancers/


https://scitechdaily.com/cracking-the-code-of-life-new-ai-model-learns-dnas-hidden-language/


https://scitechdaily.com/experimental-research-on-the-worlds-longest-living-vertebrate-reveals-new-anti-aging-secrets/


https://en.wikipedia.org/wiki/Blacktip_reef_shark


https://en.wikipedia.org/wiki/Great_white_shark


https://en.wikipedia.org/wiki/Greenland_shark

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